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National High Magnetic Field Laboratory Personnel

Dr. Arthur Scott Edison

Associate Professor, UF Biochemistry & Molecular Biology
NHMFL Director for Chemistry & Biology
UF, AMRIS Affiliated Faculty & Staff

Email:
Phone:	352 - 392-4535
Fax:	352 - 392-3422
Address:	R3-226B (Lab locations: R3-240 and R3-2) 1600 Archer Road Gainesville , FL 32610-0245

Awards, Honors & Service:
Adult Volunteer of the Year, Prairie View Elementary, Gainesville (2003)

Disclaimer: The information presented below was automatically generated from a database. In the rare instance of an exact name match, it is possible that a citation is inaccurately attributed. The listing should therefore be considered unofficial. To report a mismatched publication, contact IMsystems@magnet.fsu.edu.

Publications and Scientific Activities

##	Peer-Reviewed Publications
1	Dalisay, D.S.; Rogers, E.W.; Edison, A.S. and Molinski, T.F., Structure Elucidation at the Nanomole-Scale. Trisoxazole macrolides and Thiazole-containing cyclic peptides from the Nudibranch Hexabranchus sanguineus, J. Natural Products, 72, 732-8 (2009)
2	Dossey, A.T.; Gottardo, M.; Whitaker, J.; Roush, W.R. and Edison, A.S., Alkyldimethylpyrazines in the Defensive Spray of Phyllium westwoodii: A First for Order Phasmatodea, J. Chem. Ecol., 35 (8), 861-870 (2009)
3	Edison, A.S., C. elegans Pheromones Regulate Multiple Complex Behaviors, Current Opinion in Neurobiology, 19 (4), 378-388 (2009)
4	Kaplan, F.; Badri, D.V.; Zachriah, C.; Ajredini, R.; Sandoval, F.J.; Roje, S.; Levine, L.H.; Zhang, F.; Robinette, S.L.; Alborn, H.T.; Zhao, W.; Stadler, M.; Nimalendran, R.; Dossey, A.T.; Bruschweiler, R.A.; Vivanco, J.M. and Edison, A.S., Bacterial Attraction and Quorum Sensing Inhibition in Caenorhabditis elegans Exudates, Chem. Ecol., 35, 878-892 (2009)
5	Wang, B.; Dossey, A.T.; Walse, S.S.; Edison, A.S. and Merz, K.M. Jr., Relative Configuration of Natural Products by NMR Chemical Shifts, J. Natural Products, 72, 709-13 (2009)
6	Dossey, A.T.; Walse, S.S. and Edison, A.S., Developmental and geographical variation in the chemical defense of the walkingstick insect Anisomorpha buprestoides, J. Chem. Ecol., 34, 584-590 (2008)
7	Narayanan, R.; Genesh, O.K.; Edison, A.S. and Hagen, S.J., Kinetics of folding and binding of an intrinsically disordered protein: the inhibitor of yeast aspartic proteinase YPrA, J. Am. Chem. Soc., 130 (34), 11477-85 (2008)
8	Srinivasan, J.; Kaplan, F.; Ajredini, R.; Zachariah, C.; Alborn, H.T.; Teal, E.E.A.; Malik, R.U.; Edison, A.S.; Sternberg, P.W. and Schroeder, F.D., A blend of small molecules regulates both mating and development in Caenorhabditis elegans, Nature, 454 (7208), 1115-U46 (2008)
9	Cornnell, H.H.; Edison, A.; Grant, S.C.; Foroutan, P.; Rosenberg, J.; Sherry, A.D. and Walter, G.A., Characterization of Paramagnetic Lanthanide Ion complexes as MRI Contrast Agents as a Function of Magnetic Field Strength, Int. Soc. Mag. Reson. Med., 15, 861 (2007)
10	Dossey, A.T.; Walse, S.S.; Conley, O.V., and Edison, A.S., Parectadial, a monoterpenoid from the defensive spray of Parectatosoma mocquerysi, J. Natural Products, 70 (8), 1335-1338 (2007)
11	Edison, A.S. and Long, J. R., News and Views: "Spectroscopy: The magic of solenoids", Nature, 447 (7145), 646-647 (2007)
12	Samuel-Landtiser, M.; Zachariah, C.; Williams, C.R.; Edison, A.S. and Long, J.R., Incorporation of isotopically enriched amino acids, Current Protocols in Protein Science, 26, 26.3.1-49 (2007)
13	Woodling, K.A.; Eyler, J.R.; Tsybin, Y.O.; Nilsson, C.L.; Marshall, A.G.; Edison, A.S.; Al-Naggar, I.M. and Bubb, M.R., Identification of Single and Double Sites of Phosphorylation by ECD FT-ICR/MS in Peptides Related to the Phosphorylation Site Domain of the Myristoylated Alanine-Rich C Kinase Protein, J. Am. Soc. Mass Spectr., 18 (12), 2137-2145 (2007)
14	Zhang, F.; Dossey, A.T.; Zachariah, C.; Edison, A.S. and Bruschweiler, R., Strategy for automated analysis of dynamic metabolic mixtures by NMR. Application to an insect venom., Anal. Chem., 79 (20), 7748-52 (2007) [read online]
15	Brey, W.W.; Edison, A.S.; Nast, R.; Rocca, J.; Saikat Saha, S. and Withers, R.S., Design, Construction and Validation of a 1 mm Triple Resonance High-Temperature Superconducting Probe for NMR, J. Magn. Reson., 179 (2), 290-293 (2006) [read online]
16	Dossey, A.T.; Reale, V.; Chatwin, H.; Zachariah, C.; de Bona, M.; Evans, P.D. and Edison, A.S., Structure and Function Studies of C. elegans FLP-18 Neuropeptides: Implications in NPR-1 Activation, Biochemistry, 45 (24), 7586-97 (2006)
17	Dossey, A.T.; Walse, S.S.; Rocca, J.R. and Edison, A.S., Single Insect NMR: A New Tool to Probe Chemical Biodiversity, ACS Chemical Biology, 1 (8), 511-514 (2006)
18	Ganesh, O.K.; Green, T.B.; Edison, A.S. and Hagen, S.J., Characterizing the Residue Level Folding of the Intrinsically Unstructured IA3, Biochemistry, 45 (45), 13585-13596 (2006)
19	Li, Y.; Webb, A.; Saha, S.; Brey, W.W.; Zachariah, C. and Edison, A.S., Investigation of conductor geometry effects on the signal-to-noise of small solenoid coils for high-field protein NMR experiments, Magnet. Reson. Chem., 44 (3), 255-62 (2006) [read online]
20	Fu, R.; Brey, W.W.; Shetty, K.; Gor'kov, P.; Saha, S.; Long, J.R.; Grant, S.C.; Chekmenev, E.Y.; Hu, J.; Gan, Z.; Sharma, M.; Zhang, F.; Logan, T.M.; Bruschweiler, R.; Edison, A.; Blue, A.; Dixon, I.; Markiewicz, W.D. and Cross, T.A., Ultra-Wide Bore 900 MHz High-Resolution NMR at the National High Magnetic Field Laboratory, J. Magn. Reson., 177, 1-8 (2005) [read online]
21	Tapp, H.; Al-Naggar, I.M.; Yarmola, E.G.; Harrison, A.; Shaw, G.; Edison, A.S. and Bubb, M.R., MARCKS is a natively unfolded protein with an inaccessible actin-binding site: evidence for long-range intramolecular interactions, J. Biol. Chem., 280 (11), 9946-56 (2005)
22	Wilczynski, A.; Wilson, K.R.; Scott, J.W.; Edison, A.S. and Haskell-Luevano, C., Structure-Activity Relationships of the Unique and Potent Agouti Related Peptide (AGRP)-Melanocortin Chimeric Tyr-c[Asp-His-DPhe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 Peptide Template, J. Med. Chem., 48 (8), 3060-75 (2005)
23	Green, T.B.; Ganesh, O.; Perry, K.; Smith, L.; Phylip, L.H.; Logan, T.M.; Hagen, S.J.; Dunn, B.M. and Edison, A.S., IA3, an Aspartic Proteinase Inhibitor from Saccharomyces cerevisiae, Is Intrinsically Unstructured in Solution, Biochemistry, 43, 4071-4081 (2004) [read online]
24	Makokha, M.; Huang, Y.J.; Montelione, G.; Edison, A.S. and Barber, E., The solution structure of the pH-induced monomer of dynein light chain LC8 from Drosophila, Protein Science, 13, 727-734 (2004)
25	Schneider-Muntau, H.J.; Brandt, B.L.; Brunel, L.C.; Cross, T.A.; Edison, A.S.; Marshall, A.G. and Reyes, A.P., The National High Magnetic Field Laboratory, Physica B, 346-347, 643-648 (2004) [read online]
26	Wang, H.; Ciobanu, L.; Edison, A.S., and Webb, A.G., An eight-coil high frequency probehead design for high-throughput nuclear magnetic resonance spectroscopy, J. Magn. Reson., 170 (2), 206-212 (2004)
27	Wilczynski, A.; Wang, X.S., Bauzon, R.M.; Xiang, Z.; Shaw, A.M.; Millard, W.J.; Richards, N.G.; Edison, A.S. and Haskell-Luevano, C., Structural Characterization and Pharmacology of A Potent Bicyclic Agouti-Related Protein (AGRP) Melanocortin Receptor Antagonist, J. Med. Chem., 47, 5662-73 (2004)
28	Wilczynski, A.; Wang, X.S.; Bauzo, R.M.; Xiang, Z.; Shaw, A.M.; Millard, W.J.; Richards, N.G.; Edison, A.S. and Haskell-Luevano, C., Structural Characterization and Pharmacology of a Potent Bicyclic Agouti-Related Protein (AGRP) Melanocortin Reseptor Antagonist, J. Med. Chem., 47, 5662-73 (2004)
29	Agbandje-McKenna, M.; Edison, A.S. and McKenna, R., Biophysical Methods in Structural Biology, Essential Cell Biology, 1-Cell Structure, 269-291 (2003)
30	Li, Y.; Logan, T.; Edison, A.S. and Webb, A., Design of small volume HX and triple-resonance probes for improved limits of detection in protein NMR experiments., J. Magn. Reson., 164, 128-135 (2003) [read online]
31	Smith, L.; Zachariah, C.; Thirumoorthy, R.; Rocca, J.; Novak, J.; Hillman, J.D. and Edison, A.S., Structure and Dynamics of the Lantibiotic Mutacin 1140, Biochemistry, 42 (35), 10372-10384 (2003) [read online]
32	Edison, A.S., Theoretical Biochemistry: Processes and Properties of Biological Systems. Theoretical and Computational Chemistry 9 Edited by Leif A. Eriksson (Uppsala University). Elsevier: Amsterdam. 2001. xiv + 70, J. Am. Chem. Soc., 124 (26), 7875-7876 (2002)
33	Edison, A.S., Linus Pauling and the Planar Peptide Bond, Nature Struct. Mol. Biol., 8, 201-202 (2001)
34	Thirumoorthy, R.; Holder, J.R.; Bauzo, R.M.; Richards, N.G.J.; Edison, A.S. and Haskell-Luevano, C., Novel Agouti-Related Protein (AGRP)-Based Melanocortin-1 Receptor Antagonist, J. Med. Chem., 44, 4414-4424 (2001)
35	Yarmola, E.G.; Edison, A.S.; Lenox, R.H. and Bubb, M.R., Actin filament cross-linking by MARCKS: Characterization of two actin-binding sites within the phosphorylation-site domain, J. Biol. Chem., 276, 22351-8 (2001)
36	Zachariah, C.; Cameron, A.; Lindberg, I.; Kao, K.J.; Beinfeld, M.C. and Edison, A.S., Structural Studies of a Neuropeptide Precursor Protein with an RGD Proteolytic Site, Biochemistry, 40, 8790-8799 (2001)
37	Carlacci, L. and Edison, A., Computational Analysis of Two Similar Neuropeptides Yields Distinct Conformational Ensembles, PROTEINS: Structure, Function and Genetics, 40, 367-377 (2000)
38	Smith, L.; Novak, J.; Rocca, J.; McClung, S.; Hillman, J. and Edison, A., Covalent Structure of Mutacin 1140 and a Novel Method for the Rapid Identification of Lantibiotics, Eur. J. Biochem., 267, 6810-6816 (2000)

##	Presentations, Posters & Abstracts
1	Zhang, F.; Robinette, S.L.; Dossey, A.T. Zachariah, C.; Bruschweiler-Li, L.; Edison, A.S. and Brüschweiler, R., Covariance NMR Metabolomics Web Portal, 49th ENC Conf., Asilomar, CA, March 9-14 (2008)
2	Cornnell, H.H.; Grant, S.C.; Rosenberg, J.; Foroutan, P.; Sherry, A.D.; Edison, A. and Walter, G.A., Characterization of Paramagnetic Lanthanide Ion Complexes as MRI Contrast Agents as a Function of Magnetic Field Strength, 48th Experimental NMR Conf., Daytona, FL, April 22-28 (2007)
3	Cornnell, H.H.; Grant, S.C.; Rosenberg, J.; Foroutan, P.; Sherry, A.D.; Edison, A.S. and Walter, G.A., Characterization of Paramagnetic Lanthanide Ion Complexes as MRI Contrast Agents as a Function of Magnetic Field Strength, Joint Annual International Society for Magnetic Resonance in Medicine and European Society for Magnetic Resonance in Medicine and Biology Conference,, Berlin, Germany, May 19-25 (2007)
4	Ganesh, O.J.; Green, T.B.; Edison, A.S. and Hagen, S.J, PROTEIN FOLDING AT THE RESIDUE LEVEL: Probing NMR data with Singular Value Decomposition, 48th Experimental NMR Conf., Daytona, FL, April 22-28 (2007)
5	Zhang, F.; Brüschweiler, R.; Kaplan, F.; Zachariah, C.; Sippel, K.; Dossey, A.T. and Edison, A.S., NMR and Mixtures: New Developments for Natural Products and Metabolomics, 48th ENC, Daytona Beach, FL, April 22-27 (2007)
6	Grant, S.C.; Zheng, T.; Marshall II, G.P.; Yang, H.; Dutta, D.; Cornnell, H.; Santra, S.; Holloway, P.H.; Moudgil, B.M.; Scott, E.W.; Laywell, E.D.; Walter, G.A.; Edison, A.S.; Steindler, D.A. and Weiss, M.D., MR Microscopy of Multipotent Astrocytic Stem Cells Labeled with Multimodal Qdots Applied to a Neonatal Murine Model of Hypoxic Ischemic Encephalopathy, Int. Society of Magnetic Resonance in Medicine 14th Scientific Meeting, Seattle, WA, May 6-12 (2006); Published in Proc. Int. Society of Magnetic Resonance in Medicine, 14, 1880 (2006)
7	Saha, S.; Brey, W.W.; Withers, R.S. and Edison, A.S., Planar Coil Design for High-Temperature Superconducting 600 MHz NMR Probe, 46th ENC, Providence, RI, April 10-14 (2005)
8	Woodling, K.A.; Al-Naggar, I.; Tapp, H.; Yarmola, E.G.;Tsybin, Y.O.; Stevens, S.; Marshall, A.G; Eyler, J.R.; Edison, A.S. and Bubb, M.R., Using High Resolution Mass Spectrometry to Map Backbone Modifications of the MARCKS Protein, 53rd American Society of Mass Spectrometry Annual Conference on Mass Spectrometry & Allied Topics, San Antonio, TX, June 4-9 (2005)
9	Cross, T.A.; Edison, A.S. and Logan, T.M., NMR Spectroscopy and Imaging Facility, National High Magnetic Field Laboratory, Annual Experimental NMR Conf., Asilomar, CA, April (2002)
10	Edison, A.S.; Zachariah, C.; Antharam, V. and Thomas, S.G., Expression, Refolding, and Initial Structural Characterization of the FMRFamide-gated Sodium Channel, ENC, Asilomar, CA, April 14-19 (2002)
11	Green, T.; Perry, K.; Smith, L.; Phylip, L.H.; Logan, T.M.; Hagen, S.J.; Dunn, B.M. and Edison, A.S., IA3, A Yeast Proteinase A Inhibitor, is Intrinsically Unstructured in Solution, Miami Nature Biotechnology Symposia: The Genome and Beyond--Structural Biology for Medicine, Miami, FL, February 2-6 (2002)
12	Li, Y.; Logan, T.; Marin, V.; Brey, W.; Gor'kov, P.; Edison, A. and Webb, A., Design and Optimization of High Sensitivity Probes for Improved Limits of Detection in Protein NMR Experiments, 43rd Experimental NMR Conf., Pacific Grove, CA, April 14-19 (2002)

##	Books, Chapters, Reviews and Other One-Time Publications
1	Agbandje-McKenna, M.; Edison, A.S., and McKenna, R., "Biophysical Methods in Structural Biology", Essential Cell Biology I: A Practical Approach, Eds. J. Davey and M. Lord, Oxford University Press, in press, 2001.

##	Grants
1	PI: Blackband, S.; Edison, A.S. and Fitzsimmons, J., Grant Title: High Field Magnetic Resonance Research and Technology Agency: NIH Project Dates: 05/01/01 - 04/30/06 Award Amount: $5,150,101
2	PI: Bubb, M. and Edison, A.S., Grant Title: MARCKS-actin structure: Implications for neuroplacsticity Agency: Veteran's Administration Project Dates: 10/01/01 - 09/30/04 Award Amount: $88,000/yr
3	PI: Dunn, B.; Edison, A.S. and Hagen, S., Grant Title: Novel Inhibitors of Fungal Aspartic Proteinases Agency: NIH Project Dates: 1/1/2001 - 1/1/2004 Award Amount: $150,000/yr

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