Advanced Magnetic Resonance Imaging
and Spectroscopy
The Advanced Magnetic Resonance Imaging and Spectroscopy program (AMRIS) contains facilities for the MagLab's NMR Program that complement the facilities at the lab's headquarters in Tallahassee. AMRIS is located at the University of Florida's McKnight Brain Institute.
AMRIS houses a variety of state-of-the-art magnet systems and instruments for biological solid-state NMR, solution NMR, microimaging, animal imaging, and human imaging. AMRIS also is home to a 600 MHz, triple-resonance probe that appears to deliver the highest mass sensitivity of any probe at any frequency, enabling natural-products research when sample size is small or limited.
NMR Systems at AMRIS
|
|
Frequency
|
Field
|
Bore
|
Homogeneity
|
Measurements
|
|
750 MHz |
17.6 T
|
89 mm
|
1 ppb
|
Solution/solid State NMR and MRI
|
|
600 MHz |
14 T
|
52 mm
|
1 ppb
|
Solid State NMR and MRI
|
|
600 MHz ("Cryo600") |
14 T
|
52 mm
|
1 ppb
|
Solution NMR with cryogenically cooled 1-mm and 5-mm probes
|
|
500 MHz |
11.7 T
|
52 mm
|
1 ppb
|
Solid State/Solution NMR
|
|
470 MHz |
11.1 T
|
400 mm
|
0.1 ppm
|
MRI and NMR of animals
|
|
200 MHz |
4.7 T
|
330 mm
|
0.1 ppm
|
MRI and NMR of animals
|
|
130 MHz |
3 T
|
900 mm
|
0.1 ppm
|
MRI of humans and large animals
|
|
Animal Care Facilities
This 128 MHz, 3.0 tesla magnet joined
the AMRIS arsenal in 2007.
The AMRIS facility is approved for animal use by the Institutional Animal Care and Use Committee (IACUC). Animal use rooms undergo biannual review by UF IACUC and are maintained to the highest standards for such use. AMRIS has the industry's best noninvasive monitoring and animal care equipment. In-building animal housing is available for rodent, rabbit and feline species with remote facilities for housing large animals and primates. Veterinary and husbandry staff are available 24 hours a day. Special rooms are available for housing, veterinary care and procedures, surgery, behavior, quarantine, necropsy and various BSL requirements. The program is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC). The facility occupies 75,000 square feet of versatile and well-equipped animal care space, including operating rooms and limited radiological examination rooms.
For more information on these facilities, please visit the AMRIS Web site or contact AMRIS Director Joanna Long at jrlong@mbi.ufl.edu or (352) 846-1506.
