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ArrowIon Cyclotron Resonance (ICR) Overview


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An in-depth profile of Alan Marshall, director of the ICR program.

The National High Field Fourier Transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry facility is located at the Magnet Lab's Tallahassee headquarters. Established in 1994 by a National Science Foundation chemical instrumentation grant, the facility is charged with developing and exploiting the unique capabilities of FT-ICR mass spectrometry. The ICR program leads the world in instrument and technique development as well as pursuing novel applications of FT-ICR mass spectrometry.

Under the direction of director Alan Marshall, the ICR program continuously develops techniques and instruments and pursues novel applications of FT-ICR mass spectrometry. These methods are made available to outside scientists through the NSF National High-Field FT-ICR Mass Spectrometry Facility. The facility features directors for instrumentation, biological applications, environmental, petrochemical applications, and user services as well as a machinist, technician and seven rotating postdocs who are available to collaborate and/or assist with projects.

The facility provides service operations for sample analysis that requires the ultrahigh resolution and high mass accuracy of FT-ICR. Collaborative projects are in the areas of biomolecular analysis, hydrogen-deuterium exchange and environmental and petrochemical analysis. Four complete FT-ICR mass spectrometers are available and feature high magnetic field (currently 7, 9.4 and 14.5 T) and multiple ionization techniques (micro- and nanoelectrospray, atmospheric pressure photoionization, electron and field desorption ionization).

Latest ICR Research

Protein Sequencing from the N- and C-Termini (PowerPoint)

For more information on the ICR program, contact one of the individuals listed below:

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